A new study shows patients suffering from severe withdrawal headaches and migraines caused by drugs may benefit from high doses of aspirin.
Non-Addictive Way to Treat Medication Overuse
In the study at UCSF, participants were admitted to the hospital for severe headache complicated by medication overuse. These participants then received doses of one gram of aspirin, which is equivalent to three times the dose for typical pain relief. The medication was administered through an IV at an average of five doses. The results: 25% of the time patients reported a significant reduction in pain. Participants also reported a more modest pain reduction about 40% of the time.
Aspirin Also Shows Promise for Migraine Treatment
The patients kept hourly diaries about their pain before, during, and after treatment. They rated their pain on a 10-point scale.
“It is important to acknowledge that a placebo was not used in this case because participants knew they were receiving aspirin therapy,” Goadsby said. “However, a number of previous placebo-controlled trials have shown intravenous aspirin to be effective for migraine.”
The study is published in the journal Neurology.
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